ALS trials

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Info experimental studies

Clinical trials in Belgium...

PRECISION-ALS  Active and recruiting

QRL-201 Active and recruiting

CARDINALS Active but not recruiting

ActiSLA-studie-CHR-Citadelle-Luik Active and recruiting

AP101-studie  Active and recruiting

Corcept Therapeutics DAZALS studie met CORT113176 (dazucorilant) Active but not recruiting

Amylyx - Phoenix Completed

Studie met TPN-101 in C9orf72 ALS en/of FTD Active but not recruiting

Wave FOCUS-C9 studie met C9orf72 ASO in ALS en FTD discontinued

HIMALAYA-studie Discontinued

MAGNET-studie Active and recruiting

Cytokinetics COURAGE studie met Reldesemtiv discontinued

Ferrer ADORE studie met FAB122 (orale vorm edaravone) Active but not recruiting

Biogen ATLAS studie met ASO met presymptomatische SOD1 dragers Completed

Ionis FUSION studie met FUS ASO Active and recruiting

Apellis MERIDIAN studie met pegcetacoplan in ALS discontinued

Alexion CHAMPION-ALS studie discontinued

Orphazyme Arimoclomol (ORARIALS-01) fase III studie Completed

Biogen SOD1 ASO Completed 

Biogen Methodologie studie Completed

PESA studie Active and recruiting

PYRAMID (Phenotype Research for ALS Modifyer Discovery) studie Active and recruiting

TUDCA studie Completed

VRG50635 

Clinical trials abroad in collaboration with the league

TRICALS

 

PRODUCT STUDIE STATUS END DATE RESPONSIBLE FIRM, UNIV, CLINIC OR COUNTRY

Antiretroviral

X Recruiting   NINDS, Australia

Autologe Stamcellen

X Recruiting   US, Other countries

Allogene Stamcellen

X     Caribbean, universities
AP101-02   Recruiting 01/2025 AL-S Pharma
Cannabinoids EMERALD Active Not Recruiting 01/2024 Australia
CU(II)ATSM   Completed 12/2022 Coll Med Dev Australia
Dazucorilant DAZALS Active Not Recruiting STOP 18/11/2023 Corcept Therapeutics
Deferiprone FAIR-ALS II Recruiting 04/2022 France 
Fasudil ROCK REAL Active Not Recruiting 1/2023 Germany, France, US
GDNF   Recruiting 09/2025 Cedars Sinai
Healey Platform Trial HEALEY Active Not Recruiting 07/2024 NEALS
Ibudilast (MN-166) COMBAT-ALS Recruiting 12/2024 MediciNova
ION363 fus FUSION Recruiting 03/2028 Ionis
Lithium Magnet MAGNET Recruiting 06/2024 Tricals
Masinitib   Recruiting 12/2023 AB Science
Memantine and Trazodone SMART Recruiting 12/2026 UK
Presymptomatic sod1 ATLAS Recruiting 08/2027 ...

Biogen

PrimeC PARADIGM OLE Active Not Recruiting 11/2024 Neurosense
PTC-857 CARDINALS Active Not Recruitng 03/2025 PTC Therapeutics

Q-cells

ALTA BOLT Not Yet Recruiting 12/2025 Q Therapeutics
QRL-201   On-Hold 05/2025 QurAlis
RNS60   Not Yet Recruiting 06/2026 Italy and US
SOD1 BIIB067 Long Term   Completed 06/2024 Biogen/Ionis
TPN-101 C9 Transposon Completed 09/2023 Transposon
VRG50635   Recruiting 06/2026 Verge Genomics
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